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External RF-EMF Alters Cell Number and ROS Balance possibly via the Regulation of NADPH Metabolism and Apoptosis

Is This Technology for Cell Phone Charging Wirelessly?

Yes, the technology being discussed is primarily for wireless power transfer (WPT), which includes applications such as wirelessly charging cell phones. The 6.78 MHz ISM band is being promoted by the AirFuel Alliance specifically for mid-range wireless power transfer, which can wirelessly charge devices like mobile phones, tablets, and other consumer electronics.

Most mainstream smartphones and wireless charging accessories in the USA use the Qi wireless charging standard, which operates at different frequencies. The 6.78 MHz frequency promoted by the AirFuel Alliance is not as prevalent but represents a potential future direction for wireless charging technology. Always check the specifications of your device or consult the manufacturer for detailed information on the wireless charging frequencies supported.

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As wireless charging technology for cell phones and other devices becomes more prevalent, it is essential to consider both the thermal and non-thermal biological effects of RF-EMF exposure. The recent study on HUVEC highlights the need for updated safety guidelines and more rigorous engineering controls to ensure the safe use of 6.78 MHz for mid-range wireless power transfer. Public health guidelines must also be adjusted to reflect these new findings, ensuring that the benefits of wireless charging do not come at the expense of public health.

The study titled “External RF-EMF Alters Cell Number and ROS Balance possibly via the Regulation of NADPH Metabolism and Apoptosis” investigates the non-thermal effects of weak radio-frequency electromagnetic fields (RF-EMF) on living organisms, specifically focusing on human umbilical vein endothelial cells (HUVEC).

Human umbilical vein endothelial cells (HUVEC) are a specific type of endothelial cell that lines the interior surface of blood vessels. These cells are derived from the vein of the human umbilical cord and are commonly used in scientific research due to their accessibility and relevance in studying various aspects of vascular biology.

Here are the key findings and how bioelectricity fits into EMF health risk:

Keywords: RF-EMF radiation, mid-range wireless power transfer, cellular responses, Metabolism, Reactive Oxygen Species

Received: 29 Apr 2024; Accepted: 18 Jul 2024.

Key Findings:

  1. Non-Thermal Effects of RF-EMF:
    • The study demonstrates that weak RF-EMF can influence cellular functions without causing significant temperature changes. This challenges the current safety standards that primarily consider thermal effects.
  2. Cell Proliferation and Apoptosis:
    • RF-EMF exposure was found to promote cell proliferation and inhibit apoptosis. This indicates that RF-EMF can affect the cell cycle and survival mechanisms at a molecular level.
  3. Reactive Oxygen Species (ROS) Balance:
    • The study observed that RF-EMF exposure deregulates ROS balance within cells. ROS are crucial signaling molecules, and their imbalance can lead to oxidative stress and affect various cellular processes.
  4. Signaling Pathways and NADPH Metabolism:
    • Alterations in several signaling pathways and key enzymes involved in NADPH metabolism were identified. NADPH plays a critical role in maintaining cellular redox balance and supporting biosynthetic reactions.
  5. Ferroptosis:
    • The study highlighted the involvement of ferroptosis, a form of regulated cell death associated with iron and lipid peroxidation, in response to RF-EMF exposure.

In the USA, several smartphones and devices utilize wireless charging technology, primarily adhering to the Qi standard, which operates at different frequencies, including those within the ISM band. However, specific use of the 6.78 MHz ISM band promoted by the AirFuel Alliance for mid-range wireless power transfer isn’t as common in mainstream consumer devices as the Qi standard. Here are some devices and brands that incorporate wireless charging technology, although they may not necessarily use the 6.78 MHz frequency:

Specific Use of 6.78 MHz ISM Band:

The 6.78 MHz ISM band for wireless power transfer is more commonly associated with efforts by the AirFuel Alliance and is not yet widespread in consumer electronics compared to the Qi standard. Devices explicitly using this frequency are still emerging in the market. If you’re looking for devices using this specific standard, you may need to look for products endorsed or certified by the AirFuel Alliance, as they are the ones promoting this technology.

Role of Bioelectricity:

Bioelectricity is deeply intertwined with the findings of this study in several ways:

  1. Regulation of Cellular Functions:
    • Bioelectric signals are known to regulate cell proliferation, differentiation, and apoptosis. The study’s findings that RF-EMF promotes cell proliferation and inhibits apoptosis suggest that RF-EMF might be influencing bioelectric pathways that control these processes.
  2. ROS Balance and Bioelectricity:
    • The balance of ROS is closely linked to bioelectric states of cells. Bioelectric fields can influence redox reactions and vice versa. The deregulation of ROS balance observed in the study could be a consequence of altered bioelectric signals induced by RF-EMF.
  3. NADPH Metabolism and Bioelectricity:
    • NADPH is essential for maintaining the bioelectric gradient across cell membranes by supporting ion pump activities. Changes in NADPH metabolism could directly affect cellular bioelectricity, altering cell behavior and function.
  4. Signaling Pathways:
    • Many signaling pathways that respond to bioelectric cues are also involved in the response to RF-EMF. For instance, pathways related to ion channel regulation, membrane potential changes, and intracellular signaling cascades can be modulated by both bioelectricity and RF-EMF.
  5. Ferroptosis and Bioelectric Signals:
    • Ferroptosis involves changes in cellular iron levels and lipid peroxidation, processes that are influenced by bioelectric fields. The study’s identification of ferroptosis as a response to RF-EMF highlights a potential intersection with bioelectric regulation mechanisms.

Bioelectricity provides a framework to understand how RF-EMF can influence cellular processes beyond thermal effects. The study underscores the need to consider bioelectric mechanisms when evaluating the impact of RF-EMF on living organisms. This integration of bioelectric principles could lead to a more comprehensive understanding of RF-EMF effects and inform the development of updated safety guidelines that account for non-thermal influences.

Supporting Evidence from Major Studies

The findings from this study align with a significant body of research indicating potential health risks associated with cell phone-level electromagnetic radiation. Notable studies and reports supporting these claims include:

These studies collectively point towards an increased health risk from cell phone-level electromagnetic radiation and suggest the need for caution in dismissing potential risks.

Recognizing Therapeutic Potential of RF-EMF

While there is growing concern about the potential health risks, it’s important to acknowledge recent reviews highlighting the therapeutic potential of RF-EMF treatment. A recent review states, “Existent literature points toward a yet untapped therapeutic potential of RF-EMF treatment which might aid in damaging cancer cells through bioelectrical and electromechanical molecular mechanisms while minimizing adverse effects on healthy tissue cells.”

Advancements in RF Radiation Research

Advancements in RF radiation research have demonstrated biological interactions beyond thermal effects. For example, the FDA-approved TheraBionic treatment employs RF radiation at power levels up to 1000 times lower than those emitted by cell phones. This treatment effectively targets inoperable liver cancer through non-thermal interactions at the cellular or molecular level, including resonance effects, disruption of cellular signaling, and potential modulation of the immune system. These findings challenge the traditional view that non-ionizing cell phone radiation is biologically inert except for its heating properties.

Smartphones with Qi Wireless Charging:

  1. Apple iPhones:
    • iPhone 8 and newer models, including the iPhone SE (2020), iPhone 12 series, iPhone 13 series, and iPhone 14 series.
  2. Samsung Galaxy Phones:
    • Galaxy S6 and newer models, including the S21 and S22 series.
    • Galaxy Note 5 and newer models, including the Note 20 series.
  3. Google Pixel Phones:
    • Pixel 3 and newer models, including Pixel 5 and Pixel 6 series.
  4. LG Phones:
    • LG G6 and newer models, including LG V30 and LG V40 ThinQ.
  5. OnePlus Phones:
    • OnePlus 8 Pro and newer models, including OnePlus 9 series.

Devices with Wireless Charging:

  1. Apple AirPods:
    • AirPods Pro, AirPods (2nd generation) with wireless charging case, and AirPods (3rd generation).
  2. Samsung Galaxy Buds:
    • Galaxy Buds, Galaxy Buds+, Galaxy Buds Live, Galaxy Buds Pro, and Galaxy Buds2.
  3. Smartwatches:
    • Apple Watch Series 3 and newer models.
    • Samsung Galaxy Watch and newer models.

The Qi wireless charging standard, developed by the Wireless Power Consortium (WPC), primarily operates in the frequency range of 110 kHz to 205 kHz. This standard is widely adopted in many consumer electronics, including smartphones, smartwatches, and wireless earbuds. Here’s a more detailed breakdown:

Qi Standard Frequency Range:

Power Classes:

The Qi standard also specifies different power classes, which define the amount of power that can be transferred wirelessly. These include:

  1. Baseline Power Profile (BPP):
    • Operates at 5 watts.
    • Suitable for basic wireless charging needs, such as those for smartphones and smaller devices.
  2. Extended Power Profile (EPP):
    • Operates up to 15 watts.
    • Allows for faster charging speeds and is commonly used in modern smartphones and larger devices.

How Qi Wireless Charging Works:

Devices Using Qi Standard:

Most modern smartphones, smartwatches, and wireless earbuds from major brands like Apple, Samsung, Google, and others support Qi wireless charging. This includes devices such as:

The Qi standard has become the de facto standard for wireless charging in the consumer electronics market, providing a reliable and efficient method for powering devices without the need for physical connectors.

 

https://www.rfsafe.com/articles/cell-phone-radiation/external-rf-emf-alters-cell-number-and-ros-balance-possibly-via-the-regulation-of-nadph-metabolism-and-apoptosis.html