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New Study Shows Brain Neurodegeneration from Exposure to Cell Phone Radiation

On May 26, 2014 The Neurological Research Journal, an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences published research proving cell phone radiation does cause brain damage.

The current study led by Maheep Bhatnagar and colleagues in suggests long-term use of a cell phone can induce lipid peroxidation, lower antioxidant status, and cause neurodegeneration and impair memory and learning capability in rats.

Providing this holds true for humans; using a cell phone may not cause brain cancer in every user.  But this new study in Neurological Research suggests radiation exposure may effect most cell phone user acutely.  These effects from neurodegeneration and impaired brain functions can cause memory loss and impaired learning capability which may prove to be a more common risk  to cell phone users than brain cancer.

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For the study, rats age 30 days were exposed to 900 MHz radiofrequency which is used for in cell phones, for 4 hours per day for 15 days.  Anxiety, spatial learning, and memory were evaluated.  Brain antioxidant status and neuronal damage were also assessed.

The results support early studies conducted in Israel which found that exposure to cell phone radiation can increase oxidative stress as biomarkers of oxidation. Increased levels of reactive oxygen species were detected in the saliva of cell phone users is of great concers because high levels of reactive oxygen species may cause DNA damage and theoretically can increase risk of cancer development in some individuals.

Researchers found “A significant change in behavior, i.e., more anxiety and poor learning was shown by test animals (after exposure to mobile phone radio waves) as compared to controls and sham group.”

The control group exposed to cell phone radiation was found to have neurodegenerative cells in hippocampal sub regions and cerebral cortex.

The researchers concluded “This extensive neuronal damage results in alterations in behavior related to memory and learning.”

Additionally, Cell phone radiation exposure also significantly lowered the status of antioxidant enzymes and non-enzymatic antioxidants, and increased lipid peroxidation and the formation of reactive oxygen species.

A study in International Journal of Radiation Biology suggests that “vitamin C may play a protective role against detrimental effects of cell phone radiation on brain tissue.”

E B Imge at Department of Biochemistry, Ankara University Faculty of Medicine in Turkey and colleagues conducted the study and found vitamin C significantly increased the activity of GSH-Px and non-significantly increased the activities of 5′-NT, ADA and CAT enzymes, which were all lowered by cell phone radiation exposure (David Liu, PHD)

Official Abstract http://www.ncbi.nlm.nih.gov/pubmed/24861496

Objectives: The goals of this study were: (1) to obtain basic information about the effects of long-term use of mobile phone on cytological makeup of the hippocampus in rat brain (2) to evaluate the effects on antioxidant status, and (3) to evaluate the effects on cognitive behavior particularly on learning and memory.

Methods: Rats (age 30 days, 120 ± 5 g) were exposed to 900 MHz radio waves by means of a mobile hand set for 4 hours per day for 15 days. Effects on anxiety, spatial learning, and memory were studied using open field test, elevated plus maze, Morris water maze (MWM), and classic maze test. Effects on brain antioxidant status were also studied. Cresyl violet staining was done to access the neuronal damage.

Result: A significant change in behavior, i.e., more anxiety and poor learning was shown by test animals as compared to controls and sham group. A significant change in level of antioxidant enzymes and non-enzymatic antioxidants, and increase in lipid peroxidation were observed in test rats. Histological examination showed neurodegenerative cells in hippocampal sub regions and cerebral cortex.

Discussion: Thus our findings indicate extensive neurodegeneration on exposure to radio waves.
Increased production of reactive oxygen species due to exhaustion of enzymatic and non-enzymatic antioxidants and increased lipid peroxidation are indicating extensive neurodegeneration in selective areas of CA1, CA3, DG, and cerebral cortex. This extensive neuronal damage results in alterations in behavior related to memory and learning.

Keywords: Antioxidant enzymes, Anxiety, Behavior, Lipid peroxidation, Mobile radiations, Neurodegeneration