Inside The Sherman Paradox –
Sherman Paradox refers to a dynamic DNA mutation expressed through an anomalous pattern of inheritance in mental health disorders. The paradox was ultimately explained by insights into the mutation process that gives rise to autism spectrum disorders. It’s theorized that genes responsible for autism spectrum disorders become mutated through a two-step process. The first mutation, called the ‘premutation’, doesn’t cause any clinical symptoms.
This is typical of damage done to DNA in male sperm as a result of cell phone radiation exposure.
The epidemic rise in cases of autism causes has been blamed on pollution, drugs, genetic constraints, and occasionally immunizations.
Surprisingly, however, new research has found father’s pass on the cause 80% of autism cases and cell phone radiation exposure is now being look at as the environmental pollution affecting men which was introduced to our society around 1995, thus could be responsible for causing autism to spike since that time, and increasing to epidemic levels today.
Father’s Reproductive Cells and Healthy Babies
Men and women’s reproductive DNA is in different places. Which makes a profound difference when it comes to our close, everyday radiation exposure that began about 20 years ago.
The Specific Absorption Rate (SAR) of cell phones is a measure of the amount of radio frequency (RF) energy our bodies get when we use them. Governments set SAR limits to protect people, but governments never considered point-blank exposure to reproductive cells.
Even micro-damage to reproductive DNA can cause autism in a baby, which introduces a big question. Do studies show mobile phone radiation damages men’s reproductive cells? Yes, there are lots of studies showing this:
- “RF energy in both the power density and frequency range of mobile phones enhances mitochondrial reactive oxygen species generation by human spermatozoa, decreasing the motility and vitality of these cells while stimulating DNA base adduct formation and, ultimately DNA fragmentation.” (De Iuliis GN et al 2009)
- “We speculate that keeping the cell phone in a trouser pocket…may negatively affect spermatozoa and impair male fertility.” (Agarwal A et al 2009)
- “A recent study found that use of cell phones adversely affects the quality of semen by decreasing the sperm counts, motility, viability and morphology.” (Deepinder F et al 2007)
- “An increase in the percentage of sperm cells with abnormal morphology is associated with the duration of exposure to the waves emitted by GSM equipment.” (Wdowiak et al 2007)
- “These data suggest that EMR emitted by cellular phone influences human sperm motility. In addition to these acute adverse effects of EMR on sperm motility, long-term EMR exposure may lead to behavioral or structural changes of the male germ cell. These effects may be observed later in life, and they are to be investigated more seriously.” (Erogul O et al 2006)
- “The duration of possession and the daily transmission time correlated negatively with the proportion of rapid progressive motile sperm (r = ? 0.12 and r = ? 0.19, respectively), and positively with the proportion of slow progressive motile sperm (r = 0.12 and r = 0.28, respectively).” (Fejes I et al 2005)
- “Prolonged exposure to [cell phone] RF-EMW can also cause DNA damage…which may accelerates neuronal and spermatozoal cell death…the SAR limit (maximum acceptable exposure limit) should be lowered for cellular phones.” (Desai N et al 2009)
- “We examined 2110 men attending our infertility clinic from 1993 to October 2007…Our results showed that cell phone use negatively affects sperm quality in men.” (Gutschi T et al 2011)
- “while RFEMR does not have a dramatic impact on male germ cell development, a significant genotoxic effect on epididymal spermatozoa is evident and deserves further investigation.” (Aitken RJ et al 2005)
- “From a clinical perspective, we simply cannot ignore animal data that provide an incontrovertible link between DNA damage in spermatozoa and defects in embryonic development.” (Aitken RJ et al 2009)
- “These findings have clear implications for the safety of extensive mobile phone use by males of reproductive age, potentially affecting both their fertility and the health and wellbeing of their offspring.” (De Iuliis GN et al 2009)
Are cell phones the only cause of male reproductive DNA fragmentation, and the only cause of autism? No. But, specifically, there is only one logical source of reproductive DNA fragmentation that started for large numbers of men in developed countries across the globe about 20 years ago, leading to a sustained autism spike.
Here’s the pattern: 1) Cell phone fragments sperm cell 2) Sick sperm cell fertilizes healthy egg 3) Baby with spectrum disorder is born
Does this pass the commonsense test? Yes; the rise in autism since 1994 closely parallels the rise in autism in socioeconomic groups that gained access to cell phones since that time (rich whites first, minorities later on).
More Data
If cell phones have caused autism to soar since men began carrying cell phones around 1995, then we should expect data on mental health disorders to tell a similar story. Damaged paternal reproductive DNA would not exclusively cause autism; there would be a large spectrum of difficult-to-diagnose mental health problems in children.
Specifically, we would expect mental health disorders to have skyrocketed for children born in the last twenty years, but to be about the same for adults. In fact, based on National Ambulatory Medical Care Survey data, from 1995 to 2010, the diagnosis of mental health disorders doubled for those younger than 21, but increased by less than 6% for adults over the same period (Olfson et al 2013).
The data shows the magnitude of damaged paternal DNA stretches beyond autism. A child might inherit slightly-fragmented DNA and lose only a few IQ points; but many others that inherit moderate-to-severe fragmentation from their father will have life-long cognitive, social, and mental health problems. This could lead to social instability in public schools and across society.
Soon to be fathers who had exposed their sperm to cell phone radiation is the driving force behing The Sherman paradox!
Newborn Babies at risk from Cell Phone Radiation Exposure
A study, which involved over five years of research on children with autism and other membrane sensitivity disorders, found that cell phone radiation negatively affects cell membranes, and allows heavy metal toxins, which are associated with autism, to build up in your body.
Meanwhile, the researchers pointed out that autism rates have increased concurrently along with the proliferation of cell phones and wireless use.
Cell Phone Radiation, the researchers say, could impact autism by facilitating the early onset of symptoms or by trapping heavy metals inside nerve cells, which could accelerate the onset of symptoms of heavy metal toxicity and hinder therapeutic clearance of the toxins.
Speaking in reference to the huge rise in autism rates, the study’s co-author, said, “A rise of this magnitude must have a major environmental cause. Our data offer a reasonable mechanistic explanation for a connection between autism and wireless technology.”
They also suggest that RF Radiation from wireless devices works in conjunction with environmental and genetic factors to cause autism.
Wireless Radiation in the Etiology and Treatment of Autism (PDF Download Page)
The Sherman Paradox, first identified in Fragile X Syndrome, describes an unusual inheritance pattern in which mutations in the FMR1 gene expand over successive generations, with increasing prevalence and severity. This pattern emerges due to unstable CGG trinucleotide repeats in the FMR1 gene, which grow in size as they are transmitted, eventually crossing a threshold that triggers the disorder.
Could Wireless Radiation Drive a Similar Process?
Hypothesis: Wireless Radiation as a Catalyst for Genetic Instability
Wireless radiation, specifically radiofrequency electromagnetic fields (RF-EMFs), has been shown to induce oxidative stress, DNA damage, and epigenetic alterations. These effects could theoretically interact with regions of genetic instability, such as trinucleotide repeat sequences in FMR1 or similar loci, amplifying mutational processes akin to those observed in Fragile X syndrome.
Mechanisms Supporting This Hypothesis
- Oxidative Stress and DNA Damage:
RF-EMFs generate reactive oxygen species (ROS), leading to oxidative stress that damages DNA and hinders repair mechanisms. Regions of the genome with repetitive sequences, such as trinucleotide repeats, are particularly vulnerable to such damage. The failure to properly repair these regions could exacerbate expansions over successive generations. - Epigenetic Modifications:
Exposure to wireless radiation can alter DNA methylation patterns, potentially impacting the regulation of genes like FMR1. In Fragile X syndrome, hypermethylation of the expanded CGG repeats silences the gene, leading to the disorder. RF-EMFs might accelerate this methylation process, promoting the expansion of repeats in other genomic regions as well. - High-Prevalence Neurological Challenges:
Emerging evidence suggests that environmental factors like wireless radiation may contribute to the rise in neurodevelopmental disorders such as Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), and even cognitive decline in adults. These conditions could be driven by mechanisms similar to the Sherman Paradox, where genetic permutations accumulate due to environmental stressors, including RF-EMFs. - Cumulative Impact Across Generations:
If RF-EMFs induce repeat expansions or other genomic instabilities, these changes may not immediately manifest in observable phenotypes. However, as in Fragile X syndrome, successive generations could inherit increasingly unstable regions, eventually crossing thresholds that lead to clinical symptoms.
Evidence Linking RF-EMFs to Genetic Instability
Several studies indirectly support the possibility of RF-EMFs driving processes akin to the Sherman Paradox:
- Increased Mutation Rates:
RF-EMF exposure has been linked to increased rates of single- and double-strand DNA breaks, as well as mutations in repetitive DNA regions. These mutations could drive expansion-prone repeats to grow over generations. - Epigenetic Effects:
A 2017 study showed that RF-EMFs could alter the methylation status of specific gene promoters, suggesting a role in gene regulation and potential interactions with unstable genomic regions. - Neurological Phenotypes and RF-EMF Exposure:
The rise in neurodevelopmental disorders, including autism and ADHD, has correlated with the proliferation of wireless technologies. While causation is challenging to prove, the temporal association suggests an environmental factor contributing to genetic or epigenetic disruptions.
Broader Implications for Neurological Challenges in Society
- Intergenerational Effects:
If wireless radiation drives genetic instability, the neurological challenges we observe today may only be the beginning. Each generation could inherit progressively more unstable genomes, compounding susceptibility to neurodevelopmental disorders and cognitive decline. - Ecosystemic Impact on Reproductive Health:
Sperm and egg cells, which are particularly vulnerable to environmental insults, could accumulate mutations or epigenetic marks due to RF-EMF exposure. These germline changes might contribute to an increase in disorders with complex inheritance patterns. - Global Trends in Neurological Disorders:
As wireless technology becomes ubiquitous, the prevalence of neurodevelopmental disorders continues to rise. This pattern aligns with the hypothesis of an environmentally driven Sherman-like paradox, with RF-EMFs acting as a catalyst.
A Path Forward: Research and Action
To explore this hypothesis, the following steps are critical:
- Investigate Repetitive Genomic Regions:
Research should focus on how RF-EMFs influence trinucleotide repeats and other unstable genomic regions. Advances in next-generation sequencing can help identify patterns of expansion over time. - Epigenetic Profiling:
Epigenome-wide association studies (EWAS) can shed light on how RF-EMFs alter methylation patterns in repetitive DNA sequences, particularly in germline cells. - Longitudinal Studies:
Generational studies are essential to track changes in repeat sequences and their association with neurological phenotypes, providing direct evidence of a Sherman-like paradox driven by RF-EMFs. - Revised Safety Standards:
Regulatory bodies must update RF-EMF safety guidelines to account for non-thermal biological effects, including their potential to drive genomic instability.
Conclusion
The parallels between the Sherman Paradox in Fragile X syndrome and the potential role of RF-EMFs in driving intergenerational genetic instability present a compelling avenue for research. If confirmed, this mechanism could help explain the increasing prevalence of neurodevelopmental disorders and highlight the urgent need for safer wireless technologies. By understanding and addressing this issue, we can work to protect future generations from the unintended consequences of our technological advancements.
