In the complex environment of the human gut microbiome, where millions of microbes coexist with host cells, how do pathogenic bacteria like Salmonella Typhimurium find their way to specific sites within the gut epithelium? Recent research has unveiled a fascinating mechanism called galvanotaxis—a process where bacteria use bioelectric cues to navigate toward specific regions in […]
Gut Microbiome
The Gut Microbiome: A Bioelectricity-Driven Ecosystem Shaping Health and Disease
The study titled “Gut epithelial electrical cues drive differential localization of enterobacteria“ explores how bioelectricity within the gut epithelium influences the localization of enteric bacteria, particularly Salmonella Typhimurium and Escherichia coli. Using an ex vivo mouse caecum model, the researchers demonstrate that Salmonella preferentially targets the follicle-associated epithelium (FAE) through a process called galvanotaxis, driven […]
